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Itaconate alleviates anesthesia/medical procedures-induced cognitive impairment by activating a Nrf2-dependent anti-neuroinflammation and neurogenesis by means of intestine-brain axis Xiangyi Kong, 2017). Equally, these resulted in reduced OGT and OGA degrees in patient-derived fibroblasts and unchanged world wide protein O-GlcNAcylation as assesse